Abstract:To study the changes of nutritional status and serum biochemical indicators in elderly patients with osteoporosis (OP) complicated with sarcopenia and the relationship between them. Methods102 elderly patients with OP and sarcopenia were enrolled as observation group, and 100 healthy people with physical examination during the same period were selected as control group. The nutritional status was evaluated by mini nutritional assessment (MNA) scale, and the patients were divided into subgroups according to nutritional status results. Serum biochemical indicators of each group were detected and compared, and Pearson product-moment coefficient was used to analyze the correlation between MNA score and biochemical indicators. ResultsThe body mass index (BMI), basal metabolic rate (BMR), lumbar L2~4 bone mineral density (BMD), mid arm muscle circumference (MAMC), MNA score and levels of hemoglobin, albumin, prealbumin, triglyceride and total cholesterol in observation group were lower than those in control group (P＜0.05). Serum phosphorus in observation group was higher than that in control group (P＜0.05). The levels of serum calcium, 25-hydroxyvitamin D3, bone alkaline phosphatase (BALP) and carboxytenninal telopeptide of type I collagen (ICTP) were lower in observation group than those in control group, and the levels were significantly increased with the improvement of nutritional status (P＜0.05). MNA score was significantly positively correlated with serum calcium, 25(OH)D3, BALP and ICTP (P＜0.05). ConclusionsThe nutritional status of elderly patients with OP and sarcopenia has a significant correlation with serum biochemical indicators. Improving the nutritional status of patients may have a positive effect on controlling disease progression and improving prognosis.
