细胞膜片在骨与软骨组织修复及再生中的研究进展

Progress of cell sheet in repair and regeneration of bone and cartilage tissue

摘要:

细胞膜片技术是一种应用不同方式将细胞制备成片状的技术,该技术保留了大量的细胞外基质,在骨与软骨组织的修复与再生过程中起到了重要作用。本文将温度敏感培养法、表面修饰法、不需要任何表面修饰的制备细胞膜片的3种方式,以及细胞膜片技术在骨、软骨修复与再生领域中的研究进展及发展前景进行综述。

Abstract:

Cell sheet technology is a technique to prepare cells into sheets in different ways, which preserves a large amount of extracellular matrix and plays an important role in the repair and regeneration of bone and cartilage tissue. This paper reviews the three ways of preparing cell sheets by temperature-sensitive culture method, surface modification method, and without any surface modification, as well as the research progress and development prospects of cell sheet technology in the field of bone and cartilage repair and regeneration.