哮喘患儿支气管舒张试验与哮喘控制水平的相关性分析

Correlation between bronchial dilation test and asthma control level in children with asthma

摘要:

目的 探讨支气管舒张试验（BDT）与儿童哮喘控制水平的关系。方法 选取2016年3月至2018年3月门诊就诊的5~14岁哮喘患儿153例，根据是否为特应性体质分为过敏组（79例）和非过敏组（74例），分析两组患儿BDT与儿童哮喘控制测试量表（C-ACT）评分的相关性。结果 过敏组患儿除用力肺活量占预计值的百分比、呼气峰流量占预计值的百分比和用力呼气25%肺活量时的瞬间流量占预计值的百分比与C-ACT评分无相关性（P > 0.05）外，基础肺功能其余指标与C-ACT评分均呈正相关（P < 0.05）；非过敏组患儿基础肺功能各指标与C-ACT评分均呈正相关（P < 0.05）。除过敏组患儿用力呼气25%肺活量时的瞬间流量改善率、非过敏组患儿用力呼气50%肺活量时的瞬间流量改善率与C-ACT评分无显著相关性（P > 0.05）外，两组患儿BDT其余指标改善率与C-ACT评分均呈负相关（P < 0.05）。结论 哮喘患儿BDT改善率与C-ACT评分具有良好相关性，可作为预测哮喘控制水平的客观指标。

Abstract:

Objective To study the correlation between the bronchial dilation test(BDT)and asthma control level in children with asthma.Methods A total of 153 children with asthma,aged 5-14 years,who attended the outpatient service from March 2016 to March 2018 were enrolled.According to the presence or absence of atopic constitution,they were divided into an allergic group with 79 children and a non-allergic group with 74 children.The correlation between BDT and Childhood Asthma Control Test(C-ACT)scores was analyzed for both groups.Results All basic pulmonary function parameters were positively correlated with C-ACT scores in the non-allergic group(P<0.05).Except the forced vital capacity,peak expiratory flow and maximal expiratory flow at 25%vital capacity in percent predicted values,the other pulmonary function parameters were positively correlated with C-ACT scores in the allergic group(P<0.05).The improvement rates of all BDT parameters(except maximal expiratory flow at 25%vital capacity in the allergic group and maximal expiratory flow at 50%vital capacity in the non-allergic group)were negatively correlated with C-ACT scores in the two groups(P<0.05).Conclusions The improvement rate of BDT is well correlated with C-ACT scores in children with asthma,suggesting that BDT can be used as an index for predicting asthma control level.