维生素D在儿童肠易激综合征中的作用

Role of vitamin D in pediatric irritable bowel syndrome

摘要:

肠易激综合征（IBS）是一种儿童常见的功能性胃肠病，临床表现以反复腹痛伴排便频率或大便性状的改变为特征。多项研究表明，IBS患儿维生素D水平显著低于健康人群，且补充维生素D能明显改善IBS患儿的临床症状和生活质量，提示维生素D可能对IBS有治疗作用。该综述主要讨论维生素D与儿童IBS的关系，并就其可能的作用机制进行阐述。

Abstract:

Irritable bowel syndrome(IBS)is a common functional gastrointestinal disease in children and has the clinical manifestations of recurrent abdominal pain with the changes in defecation frequency or stool form.Many studies have shown that children with IBS have a significantly lower vitamin D level than the healthy population,and vitamin D supplementation can significantly improve the clinical symptoms and quality of life of the children,suggesting that vitamin D supplementation may play a role in the treatment of IBS.This article reviews the association between vitamin D and IBS in children and elaborates on the possible mechanism of action of vitamin D.