围生期常用治疗对子代神经发育影响的研究进展

Recent research on the effect of common treatments given in the perinatal period on neurodevelopment in offspring

摘要:

围生期是子代大脑及中枢神经发育的关键时期，此期内发生的不同事件都会对子代大脑的发育进程有着深远影响。糖皮质激素、抗生素、硫酸镁、咖啡因、肺表面活性物质及亚低温治疗等是围生期的常见治疗药物及手段，与新生儿的神经发育预后有着密切关系。该文总结近年围生期治疗对新生儿神经发育影响的最新研究进展，为临床决策提供参考。 引用格式：中国当代儿科杂志，2022，24（3）：332-338

Abstract:

The perinatal period is the key period for the development of brain and central nervous system, and different events in this period will have a profound influence on brain development. Glucocorticoids, antibiotics, magnesium sulfate, caffeine, pulmonary surfactant, and mild hypothermia treatment are commonly used drugs or treatment methods in the perinatal period and are closely associated with the prognosis of neonatal neurodevelopment. This article reviews the latest research on the effect of perinatal treatments on neonatal neurodevelopment, so as to provide a reference for clinical decision making.