新生儿经外周静脉穿刺的中心静脉导管相关血栓1例

Peripherally inserted central venous catheter-related thrombosis in a neonate

摘要:

患儿女，生后4 h，因早产、生后呼吸困难4 h入院。患儿生后第3天行经外周静脉穿刺的中心静脉导管（peripherally inserted central venous catheter，PICC）置管。生后第42天心脏彩超示下腔静脉右心房入口处血栓，考虑PICC置管相关血栓形成。予以低分子肝素抗凝、尿激酶溶栓等治疗。治疗2周后心脏彩超提示血栓缩小。病程中未出现出血、肺动脉栓塞等并发症。患儿好转出院。该文主要介绍新生儿PICC置管相关血栓的多学科诊疗。

Abstract:

The female infant in this case study was admitted to the hospital 4 hours after birth due to preterm birth and respiratory distress. On the third day after birth, peripherally inserted central venous catheter (PICC) catheterization was performed. On day 42, thrombus was found at the entrance of the right atrium from the inferior vena cava during a cardiac ultrasound, and it was considered to be related to PICC placement. Low-molecular-weight heparin and urokinase were given. After two weeks of treatment, ultrasonic monitoring showed thrombus shrinkage. No bleeding or pulmonary embolism occurred during the treatment. The patient discharged after improvement. This article mainly introduces a multidisciplinary team approach to diagnosis and treatment of PICC-related thrombosis in neonates.