胆囊神经内分泌癌的研究进展

Research progress of gallbladder neuroendocrine carcinoma

摘要:

胆囊神经内分泌癌（GB-NEC）在临床上较为罕见，近年来，在GB-NEC的术前影像学诊断、生存预测以及治疗等方面研究已经取得了一些进展。在临床实践中，应考虑到不同患者病情的差异性和不同的治疗方案的疗效，以提供最佳的个体化治疗方案。笔者回顾近年来GB-NEC的临床及基础研究，结合国内外对GB-NEC的病例报道及其他相关文献，对GB-NEC的发病机制、病理学分型、诊断、治疗进展和预后进行综述。

Abstract:

Gallbladder neuroendocrine carcinoma (GB-NEC) is a rare clinical entity. In recent years, some advances have been made in terms of preoperative imaging diagnosis, survival prediction and treatment of GB-NEC. In clinical practice, the different patients' conditions and the efficacy of different treatment schemes should be taken into account to provide the most appropriate individualized treatment plan. Here, the authors review the clinical and basic research of GB-NEC in recent years, and summarize the pathogenesis, pathological classification, diagnosis, treatment progress and prognosis of GB-NEC based on the literature of case report of GB-NEC and other relevant data.