Abstract:Platinum drugs are currently widely used in the chemotherapy of gynecological tumors. As a derivative of cisplatin, carboplatin is a second-generation platinum-based anticancer drug with the characteristics of "equipotency" and "low toxicity". Hypersensitivity reactions to carboplatin are common complications during its treatment, but acute severe hypersensitivity reactions can endanger the lives of patients. Therefore, prevention of carboplatin-induced hypersensitivity, timely diagnosis of hypersensitivity reactions and proper treatments are important to improve the overall efficacy of carboplatin antitumor therapy and to reduce the risk of mortality. Hence, here comes the consensus on hypersensitivity reactions induced by carboplatin chemotherapy of gynecologic tumors in China (2022 edition), aiming to provide guidelines for clinical practitioners and to standardize treatment behaviors.
